We are pleased to provide an update on the Global Schools of Neuroimmunology (GSNI), an exciting initiative of the International Society of neuroimmunology (ISNI) that was started in 2015. While the European School of Neuroimmunology (ESNI) has been running annually since 2000, schools of neuroimmunology were not readily available in other parts of the globe. To address this deficit, and to continue to grow the rapidly evolving and transformative neuroimmunology principles that affect all neurological conditions, ISNI set out to create schools elsewhere. Thus, the inaugural Americas School of Neuroimmunology (ASNI) was held in Calgary, Canada on October 1-2, 2015, which was co-hosted by Professors V. Wee Yong (Canada) and Phil Popovich (USA). The School was attended by 150 delegates from the North, Central and South America. Several travel awards were made available particularly to those from Central and South Americas.