Dr. Markus Hofer MD, Privatdozent

Markus Hofer is a clinical and experimental neuropathologist. He obtained his MD in 2001 at the University of Freiburg, Germany. After a postdoctoral period in the department of neuropathology at Freiburg University Hospital, Markus joined the laboratory of Professor Iain Campbell at the University of Sydney in 2005 to study the role of non-canonical type I interferon signalling in neuroinflammation. In 2008 he returned to Germany and in 2010 became Senior Consultant and Privatdozent in the Department for Neuropathology at the University Hospital in Marburg. In 2013 he returned to the University of Sydney as Lecturer for Molecular Biology and Genetics. Markus is also an honorary member of the Department of Neuropathology at the Royal Prince Alfred Hospital in Sydney and works as a neuropathologist for the New South Wales Tissue Resource Centre and the Sydney Brain Bank. Markus has published 45 papers and has been cited more than 800 times.


The focus of Markus’ research are the molecular mechanisms behind the pleiotropic actions of cytokines in the CNS. He is particularly interested how type I interferons and interleukin-6 contribute to neuroinflammatory and neurodegenerative diseases in the brain. For this, Markus’ laboratory uses a number of different in vivoand in vitromodels for viral encephalitis, autoimmune and autoinflammatory diseases.