Dr. Michael Jackson PhD

Dr Michael Jackson is an academic with a research interest in Autoimmunity, particularly the pathogenic mechanisms of functional autoantibodies. His work on functional autoantibodies includes type 1 diabetes, where he discovered an autoantibody to voltage-gated calcium channels, which disrupts extracellular calcium flux in visceral smooth muscle, resulting in autonomic dysfunction, and stress induction in pancreatic beta cells. Additionally, he has demonstrated the presence of functional anti-neuronal antibodies in human narcolepsy with cataplexy. He has developed cell-based assays for the detection of the anti-channel antibody in type 1 diabetes, and for anti-muscarinic receptor antibodies in Sjögrens Syndrome.  His work has been the subject of articles by Reuters News, The Sydney Morning Post and Melbourne Age, and has been sited by SciBX Nature, and he has published in the Lancet, Gastroenterology, Journal of Neuroscience and Arthritis & Rheumatism.  His current research includes the functional implications of autoantibodies in type 1 diabetes and narcolepsy, and proteomic analysis of autoantibodies in both systemic and organ confined autoimmunity.