Prof. Dr. Waisman graduated in Life Sciences at the University of Tel-Aviv, Israel, in 1986. From 1986 until 1989, he made his Master in Science at the department of Molecular Genetics at the Weizmann Institute of Science, Rehovot, Israel. He then continued for PhD in the same institute, at the Department of Immunology, under the supervision of Prof. Edna Mozes studying a mouse model for systemic lupus erythematosus. The PhD finished in 1994, and he moved to make his first post doctorate study under the supervision of Prof. Lawrence Steinman from Stanford Medical School studying the mechanism of DNA vaccination in a mouse model of Multiple Sclerosis and implementing the research in order to treat the mice. In the year 1996 he moved for a second post doctorate period to Cologne, Germany, where he generated different mouse models to study autoimmunity under the supervision of Prof. Dr. Klaus Rajewsky. In 2001 he became an independent group leader in the Institute of Genetics in Cologne where he continued to study autoimmunity using the technique of conditional gene targeting. In April 2005 he moved to Mainz as he was nominated an Associate Professor for Pathophysiology. In 2011 he became the Head of the Institute for Molecular Medicine in the University Medical Center Mainz.