Prof. Frauke Zipp MD
Department of Neurology
Focus Program Translational Neurosciences (FTN) and Immunotherapy (FZI)
Rhine-Main Neuroscience Network (rmn²)
University Medical Center of the Johannes Gutenberg
University Mainz
Mainz | Germany

Following medical studies at Goethe University in Frankfurt am Main as well as in the USA, Canada and England, Frauke Zipp was a junior doctor in the Department of Neurology at Goethe University in Frankfurt and at Eberhard Karls University in Tübingen. She began to specialize in neuroimmunology during a postdoc at the Max Planck Institute (MPI) in Martinsried/Munich with Prof. Wekerle and Prof. Hohlfeld, and as visiting scientist at the National Institutes of Health (NIH) in Bethesda, Maryland, USA. From 2002, Frauke Zipp was a Professor at Charité in Berlin and, four years later in response to an offer as neurology chair at Queen Mary, London, UK, was promoted to senior professor and director of the Cecilie-Vogt Clinic, Charité, and appointed clinical coordinator in the governance board of the Max Delbruck Center for Molecular Medicine (MDC) in Berlin. She has been Director of the Department of Neurology at the Johannes Gutenberg University in Mainz since the end of 2009.

Prof. Zipp is a member of the international medical and scientific board of the Multiple Sclerosis International Federation (MSIF), the advisory board for technology to the government of Rhineland-Palatinate, and rapporteur for the Max Planck Society. She is on the executive board of the German Competence Network of Multiple Sclerosis (KKNMS) and the medical advisory board of the German Multiple Sclerosis Society (DMSG), was in the council of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) as well as a member of the advisory board for the International Society for Neuroimmunology (ISNI).

She has continually made successful applications for funding from international and national research councils, foundations and industry as well as published over 300 scientific peer-reviewed papers. She is the founding speaker of two trans-regional collaborative research centers and, together with four colleagues, founding member of a German Research Foundation (DFG) excellence cluster. In addition, Frauke Zipp is member of the German National Academy of Sciences Leopoldina and the European Academia Europaea. Her work focuses on inflammatory neuronal damage and repair in multiple sclerosis, with an emphasis on therapy, as well as more general questions on the crosstalk between the nervous and immune systems.

Selected 5 papers in past 2 years

  • Pape K, … Zipp F (2019) Immunoneuropsychiatry – novel perspectives on brain disorders. Nat Rev Neurol 15: 317-328
  • Birkner K, … §Zipp F, §Bittner S (2019) β1-integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells. J Clin Invest 126381, epub ahead of print, §equally contributing and corresponding
  • Vogelaar CF, … Zipp F (2018) Fast direct neuronal signaling via the IL-4 receptor as therapeutic target in neuroinflammation. Sci Transl Med, 10(430)
  • Ellwardt E, … §Zipp F, §Stroh A (2018) Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nat Neurosci, 21: 1392-1403, §equally contributing and corresponding
  • Larochelle C, … Zipp F (2018) EGFL7 reduces CNS inflammation in mouse. Nat Commun, 9: 819