Dr. Bergmann’s research focuses on innate and adaptive immune responses using a neurotropic coronavirus (mouse hepatitis virus; MHV) model of acute infection resolving into persistence associated with demyelinating disease. She received her PhD in Chemical Engineering in Germany and pursued postdoctoral studies in rotavirus assembly in New Zealand.  She expanded her research to study the pathogenesis of neurotropic coronavirus infections during her time at the University of Southern California and now at the Cleveland Clinic.   Her research  has provided insights into glia-specific innate responses and the regulation of T and B cells within the CNS in vivo. Current studies focus on a) the role of meningeal stromal cell activation in regulating B cells in the CNS, b) T-cell instruction of microglia/macrophage demyelinating function, and c) anti-inflammatory mechanisms containing pathology.