Prof. Sarosh Irani BMBCh, MA (Oxon) DPhil FRCP
Department of Neurology
Oxford University Hospitals NHS Foundation Trust
Oxford Autoimmune Neurology Group
Nuffield Department of Clinical Neurosciences
- Professor of Autoimmune Neurology
- Head, Oxford Autoimmune Neurology Group, Research laboratory
- MRC Senior Clinical Fellow
- Honorary Consultant Neurologist
- Associate Editor @Brain
Sarosh Irani is a clinician scientist, Professor of Autoimmune Neurology and consultant neurologist, at the University of Oxford. He and his group are excited to be moving to the Mayo Clinic, Florida, from Summer 2023.
His work aims to improve treatments and outcomes for patients with autoantibody-mediated diseases of the nervous system and understand the biology behind these rapidly expanding group of conditions.
Clinically, he runs the UK’s major clinic for autoantibody related CNS diseases and described faciobrachial dystonic seizures, in association with LGI1-antibodies, the importance of early immunotherapy in these patients, and distinctive psychopathological features associated with NMDAR-antibody encephalitis. In the laboratory, he has led the discovery of LGI1- and CASPR2-antibodies, their associated HLA associations and the roles of B cells in the pathogenesis of autoimmune forms of encephalitis and neuromyelitis optica.
He was awarded the Graham-Bull Prize in Clinical Science / Goulstonian Lectureship, from the Royal College of Physicians, and awards including the NIHR BRC Senior Clinical Fellowship, International Society of Neuroimmunology Clinical Science Prize and both Wellcome Intermediate and MRC Senior Clinical Fellowships.