Day 3 | August 22
ISNI DAY 2 - MONDAY AUGUST 21 |
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WELCOME & INTRODUCTION8:00am - 8:30am |
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| Welcome Remarks Luc Vallières (Canada) & LOC ISNI President Francisco Quintana (USA) Introduction: current challenges in Neuroimmunology Jack Antel (Canada) |
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PLENARY SESSION 18:30am - 10:00am |
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| Neuroimmune interactions in neural development, cognition, and homeostasis Chairs: Oleg Butovsky (USA) & Serge Rivest (Canada) 8:30am-9:00am | Microglia functions from development to neurodegeneration Florent Ginhoux (Singapore) 9:00am-9:30am | Immunoception: central representation and regulation of immunity Asya Rolls (Israel) 9:30am-10:00am | Unexpected interactions of the immune and nervous system - relevance for disease Frauke Zipp (Germany) |
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| Coffee Break | 10:00am-10:30am | ||
MORNING BREAKOUT SESSIONS10:30am - 12:00pm |
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| Inflammation in neurodegenerative diseases Chairs: Li Gan (USA) & Serge Rivest (Canada) 10:30am-10:48am | Gut neuroimmune interaction impacts brain synucleinopathy in Parkinson’s disease models Soyon Hong (UK) 10:48am-11:06am | Decoding chronic inflammation in multiple sclerosis Martina Absinta (Italy) Oral Presentations 11:06am-11:24am | #137 The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease Aurélie de Rus Jacquet (Canada) 11:24am-11:42am | #154 Meningeal Lymphatics dysfunction disturbs cortical E/I balance Kyungdeok Kim (USA) 11:42am-12:00pm | #51 A CD8 T cell signature in amyotrophic lateral sclerosis 4 Laura Campisi (USA) | Autoantibodies in neurological conditions Chairs: Luc Valliéres (Canada) & Roland Liblau (France) 10:30am-10:48am | The B cell immunology underlying autoantibody-mediated CNS diseases Sarosh Irani (UK) 10:48am-11:06am | Autoimmune encephalitis and dementia – new disease concepts Harald Prüss (Germany) 11:06am-11:24am | The cow conundrum – Novel insights into antibody-mediated disease mechanisms in multiple sclerosis Stefanie Kuerten (Germany) Oral Presentations 11:24am-11:42am | #197 The emerging spectrum of foetal acetylcholine receptor antibody-related disorders (FARAD) Angela Vincent (UK) 11:42am-12:00pm | #276 Anti-Ganglioside (Complex) Antibodies In Patients From The International Guillain-Barré Syndrome Outcome Study Robin C. M. Thomma (the Netherlands) |
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| Sponsored Lunch Break Symposium by EMD Serono - 12:00pm-1:00pm | ||
| EMD Serono Sponsored Symposium | Evolving Concepts in Multiple Sclerosis Disease Progression: The impact of peripheral and centrally-driven neuroinflammation Click on title for more information 12:15pm-12:20pm Welcome Dr V. Wee Yong 12:20pm-12:30pm Neuropathological mechanisms in peripherally and centrally-derived inflammation in MS Dr. V. Wee Yong 12:30pm-12:40pm The evolving clinical course of MS and its impact on disability progression Dr Jiwon Oh 12:40pm-12:50pm Emerging fluid biomarkers of MS disease progression Dr. Raphael Schneider 12:50pm-1:00pm Audience Q&A Dr. V. Wee Yong & Faculty | ||
AFTERNOON BREAKOUT SESSIONS1:00pm - 3:00pm |
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| Non-MS autoimmune diseases Chairs: Stefanie Kuerten (Germany) & Raphael Schneider (Canada) 1:00pm-1:15pm | Waking up to the immunology of Narcolepsy type 1 Roland Liblau (France) 1:15pm-1:30pm | Mechanisms governing autoantibody-mediated pathology in autoimmune neurologic diseases Kevin O'Connor (USA) 1:30pm-1:45pm | Immunopathology of NMOSD and MOGAD Kazuo Fujihara (Japan) Oral Presentations 1:45pm-2:00pm | #42 Autoantibody effector functions in MOGAD Soumya S. Yandamuri (USA) 2:00pm-2:15pm | #337 Regulation of Th17 and B cells by interferon-gamma in a novel Neuromyelitis Optica Disease Spectrum Disorder animal model Gabriel Arellano (USA) 2:15pm-2:30pm | #251 Pathogenic complement activation in myasthenia gravis depends on affinity matured autoantibodies with synergistic subunit specificities Sebastian Holdermann (Switzerland) 2:30pm-2:45pm | #261 Single-cell phenotyping of B cells to investigate Rituximab response in patients with Myasthenia Gravis Jacopo Morroni (Italy) 2:45pm-3:00pm | #3 The emerging role of autoreactive T cells in Guillain-Barré syndrome Lenka Súkeníková (Switzerland) | Psychoneuroimmunology Chairs: Jessica Deslauriers (Canada) & Frauke Zipp (Germany) 1:00pm-1:15pm | Immune-Brain Interactions in Depression Scott Russo (USA) 1:15pm-1:30pm | Sex-specific brain and gut barrier alterations underlie stress vulnerability vs resilience in mice and human depression Caroline Menard (Canada) 1:30pm-1:45pm | Using circadian neuroimmunology to dissect molecular, cellular, and functional outcomes in health and disease Nader Ghasemlou (Canada) Oral Presentations 1:45pm-2:00pm | #300 The presence of antibodies against muscarinic acetylcholine receptors in people with first episode psychosis predicts a worse clinical outcome at 12 months follow-up Judith Greer (Australia) 2:00pm-2:15pm | #142 Interaction between a high fat diet and stress: effect on depression in relation to the gut microbiome-endocannabinoidome axis Giada Giorgini (Canada) 2:15pm-2:30pm | Behavioral as well as hippocampal transcriptomic and microglial responses differ across sexes in adult mouse offspring exposed to a dual genetic and environmental challenge Micaël Carrier (Canada) 2:30pm-2:45pm | #172 Psychological stress exacerbates immunoglobulin E-dependent chronic allergic skin inflammation via suppression of M2 macrophage-induced efferocytosis Soichiro Yoshikawa (Japan) 2:45pm-3:00pm | #400 Neurovascular mitochondrial susceptibility impacts blood-brain barrier function and behavior Jorge Alvarez (USA) | Learning about Neuroimmunology through MS Sponsored by ACTRIMS Chairs: Jacqueline Quandt (Canada) & Burkhard Becher (Switzerland) 1:00pm-1:24pm | An unexpected role of B cells in neuromyelitis optica Thomas Korn (Germany) 1:24pm-1:48pm | Age-sensitive immune markers in multiple sclerosis: relation to biological sex and treatment response Catherine Larochelle (Canada) 1:48pm-2:12pm | Decoding and targeting cell type-specific signatures underlying progressive neuroinflammation Lucas Schirmer (Germany) 2:12pm-2:36pm | The Impact of Aging on Glia and Neuroinflammation: Implications for MS and EAE Benjamin Segal (USA) 2:36pm - 3:00pm | Microglia in multiple sclerosis – pathogenesis and imaging Laura Airas (Finland) |
ISNI KEYNOTE LECTURE3:15pm - 4:15pm |
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| The Dale McFarlin Lecture Chair: Jack Antel (Canada) Tackling Heterogeneity in Multiple Sclerosis: On Path to Precision Neuroimmunology Amit Bar-Or (USA) |
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POSTER SESSION 14:15pm - 6:15pm Autoantibodies in neurological conditions |
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Welcome Cocktail6:15pm - 7:15pm | ||