8:00am - 10:00am
Neuroinflammation in degenerative diseases
Malu Tansey (USA) & Jean-Pierre Julien (Canada)

8:00am-8:30am | TBD
Michael Heneka (Germany)

8:30am-9:00am | Neuroimmune modulation by AD risk genes
Li Gan (USA)

9:00am-9:30am | Honing in on the molecular orchestrators of neuroprotective microglial responses in Alzheimer’s disease
John R. Lukens (USA)

9:30am-10:00am | Brain-Immune ecosystem and immunotherapy to defeat dementia
Michal Schwartz (Israel)
Coffee Break 10:00am-10:30am


10:30am - 12:00pm
CNS barriers
Britta Engelhardt (Switzerland) & Jorge Alvarez (USA)

10:30am-10:48am | Regulation of the blood-brain barrier in health and disease
Richard Daneman (USA)

10:48am-11:06am ! Ependymal cell dysregulation during neuroinflammatory events
Jo Anne Stratton (Canada)

11:06am-11:24am | Brain endothelial cells under inflammatory challenge
Alexandre Prat (Canada)

Oral Presentations
11:24am-11:42am | #243 Cerebral microangiopathy is a key mediator of interferon-alpha neurotoxicity
Barney Viengkhou (Australia)

11:42am-12:00pm | #127 CRTAM-Necl2 interaction at the glia limitans triggers astrogliosis and protection against EAE
Bieke Broux (Belgium)
Infection and neuroinflammation
Louis Flamand (Canada) & William Robinson (USA)

10:30am-10:48am | Innate immune mechanisms in neurological disease: lessons from neuroHIV and COVID-19
Christopher Power (Canada)

10:48am-11:06am | Mononuclear Cell Triggers of Learning and Memory Impairment : Viral effects on Integrated Systems
Robyn Klein (USA)

11:06am-11:24am | B cell dynamics during murine neurotropic coronavirus infection
Cornelia Bergmann (USA)

Oral Presentations
11:24am-11:42am | #64 Trichinella spiralis promotes neuroimmune remodeling that ameliorates disease in a mouse model of multiple sclerosis
Naomi M. Fettig (Canada)

11:42am-12:00pm | #330 Sepsis, complement, and microglial synaptic pruning: findings in the mouse and human brain
Kate A. Giffin (USA)
Lunch Break & Novartis Sponsored Symposium (starts at 12:15pm) 12:00pm-1:00pm
Novartis Sponsored Symposium | From the Bedside to the Bench... and Back Again!
Dr. Catherine Larochelle (Canada)

Dr Amit Bar-Or (USA)

Dr. Virginia Devonshire (Canada)


1:00pm - 3:00pm
From basic to translational and clinical Neuroimmunology: contributions from young scientists - sponsored by JNI
Veit Rothhammer (Germany), Aakanksha Dixit (Australia), Jeff Dong (Canada), Naomi Habib (Israel), Hedwich Kuipers (Canada), Olga Rojas (Canada) & Michal Wheeler (USA)

1:00pm-1:15pm | Introduction
ISNI Young Committee & JNI

1:15pm-1:30pm | The road not taken - cellular cascades in Alzheimer’s and aging
Noami Habib (Israel)

1:30pm-1:45pm | Protective glia crosstalk in autoimmune CNS inflammation
Lena Lößlein (Germany)

1:45pm-2:00pm | Impaired central tolerance characterises the early emergence of AQP4-specific B cells in neuromyelitis optica spectrum disorder
Sudarshini Ramanathan (Australia)

2:00pm-2:15pm | Immune regulation of stress
Chao Wang (Canada)

2:15pm-2:30pm | Understanding the role of B cells in neurodegeneration
Olga Rojas (Canada)

2:30pm-2:45pm | The neural circuits controlling sickness behavior
Jessica Osterhout (USA)

2:45pm-3:00pm | Discussion
Peripheral Neuroimmunology
Nader Ghasemlou (Canada) & Phillip Popovich (USA)

1:00pm-1:15pm | Nociceptor neuron recognition of microbes in host defense and immunity
Isaac Chiu (USA)

1:15pm-1:30pm | Pain neurons control cancer immunosurveillance
Sebastien Talbot (Canada)

1:30pm-1:45pm | Neuro-immune interactions in the gut
Daniel Mucida (USA)

Oral Presentations
1:45pm-2:00pm | 13 Multimodal control of dendritic cell functions by nociceptors
Pavel Hanč (USA)

B cells in Neuroinflammation
Chairs: Amit Bar-Or (USA) & Heinz Wiendl (Germany)

2:00pm-2:15pm | Plasmablasts in a model of CNS autoimmunity: from biology to therapy
Luc Vallières

2:15pm-2:30pm | #345 T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity
Anneli Peters (Germany)

2:30pm-2:45pm | #44 T-bet+ Memory B Cells Induce Disease Relapses in Experimental Autoimmune Encephalomyelitis
Rajiv Jain (Canada)

2:45pm-3:00pm | #55 B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice
Angela A. Wang (Canada)
Learning about Neuroimmunology through ALS - Sponsored by ALS Society of Quebec
Chrstine Vande Velde (Canada) & Jean-Pierre Julien (Canada)

1:00pm-1:20pm | The title of my talk will be: Microglia and macrophages for ALS progression.
Séverine Boillée (France)

1:20pm-1:40pm | Modulating myeloid cells in ALS by targeting α5 integrin
Bahareh Ajami (USA)

1:40pm-2:00pm | Targeting innate immune genes translation in ALS
Jasna Kriz (Canada)

2:00pm-2:20pm | Peripheral and resident immune cells crosstalk in ALS
Cristina Limatola (Italy)

2:20pm-2:40pm | Role of endogenous retroviruses in Amyotrophic Lateral Sclerosis
Avindra Nath (USA)

2:40pm-3:00pm | Restoring glial functions at the neuromuscular synapse: a clinical target in ALS
Richard Robitaille (Canada)


3:15pm - 4:15pm
The Immunology Lecture
Francisco Quintana (USA)

Checkpoints of CNS autoimmunity: from the perspective of an autoaggressive T cell
Alexander Flügel (Germany)


4:15pm - 6:15pm

CNS barriers
CNS-infiltrating innate immune cells
Emerging therapies for neuroinflammatory conditions
Infection and neuroinflammation
Influence of diet and microbiota on neuroinflammation
Neuroimmunology general II
Novel approaches for neuroimmunologists