ISNI DAY 4 | WEDNESDAY AUGUST 23 |
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PLENARY SESSION8:00am - 10:00am |
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| Neuroinflammation in degenerative diseases Chairs: Malu Tansey (USA) & Jean-Pierre Julien (Canada) 8:00am-8:30am | TBD Michael Heneka (Germany) 8:30am-9:00am | Neuroimmune modulation by AD risk genes Li Gan (USA) 9:00am-9:30am | Honing in on the molecular orchestrators of neuroprotective microglial responses in Alzheimer’s disease John R. Lukens (USA) 9:30am-10:00am | Brain-Immune ecosystem and immunotherapy to defeat dementia Michal Schwartz (Israel) |
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| Coffee Break 10:00am-10:30am | ||
MORNING BREAKOUT SESSIONS10:30am - 12:00pm |
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| CNS barriers Chairs: Britta Engelhardt (Switzerland) & Jorge Alvarez (USA) 10:30am-10:48am | Regulation of the blood-brain barrier in health and disease Richard Daneman (USA) 10:48am-11:06am ! Ependymal cell dysregulation during neuroinflammatory events Jo Anne Stratton (Canada) 11:06am-11:24am | Brain endothelial cells under inflammatory challenge Alexandre Prat (Canada) Oral Presentations 11:24am-11:42am | #243 Cerebral microangiopathy is a key mediator of interferon-alpha neurotoxicity Barney Viengkhou (Australia) 11:42am-12:00pm | #127 CRTAM-Necl2 interaction at the glia limitans triggers astrogliosis and protection against EAE Bieke Broux (Belgium) | Infection and neuroinflammation Chairs: Louis Flamand (Canada) & William Robinson (USA) 10:30am-10:48am | Innate immune mechanisms in neurological disease: lessons from neuroHIV and COVID-19 Christopher Power (Canada) 10:48am-11:06am | Mononuclear Cell Triggers of Learning and Memory Impairment : Viral effects on Integrated Systems Robyn Klein (USA) 11:06am-11:24am | B cell dynamics during murine neurotropic coronavirus infection Cornelia Bergmann (USA) Oral Presentations 11:24am-11:42am | #64 Trichinella spiralis promotes neuroimmune remodeling that ameliorates disease in a mouse model of multiple sclerosis Naomi M. Fettig (Canada) 11:42am-12:00pm | #330 Sepsis, complement, and microglial synaptic pruning: findings in the mouse and human brain Kate A. Giffin (USA) |
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| Lunch Break & Novartis Sponsored Symposium (starts at 12:15pm) 12:00pm-1:00pm | ||
| Novartis Sponsored Symposium | From the Bedside to the Bench... and Back Again! Chair: Dr. Catherine Larochelle (Canada) Dr Amit Bar-Or (USA) Dr. Virginia Devonshire (Canada) | ||
AFTERNOON BREAKOUT SESSIONS1:00pm - 3:00pm |
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| From basic to translational and clinical Neuroimmunology: contributions from young scientists - sponsored by JNI Chairs: Veit Rothhammer (Germany), Aakanksha Dixit (Australia), Jeff Dong (Canada), Naomi Habib (Israel), Hedwich Kuipers (Canada), Olga Rojas (Canada) & Michal Wheeler (USA) 1:00pm-1:15pm | Introduction ISNI Young Committee & JNI 1:15pm-1:30pm | The road not taken - cellular cascades in Alzheimer’s and aging Noami Habib (Israel) 1:30pm-1:45pm | Protective glia crosstalk in autoimmune CNS inflammation Lena Lößlein (Germany) 1:45pm-2:00pm | Impaired central tolerance characterises the early emergence of AQP4-specific B cells in neuromyelitis optica spectrum disorder Sudarshini Ramanathan (Australia) 2:00pm-2:15pm | Immune regulation of stress Chao Wang (Canada) 2:15pm-2:30pm | Understanding the role of B cells in neurodegeneration Olga Rojas (Canada) 2:30pm-2:45pm | The neural circuits controlling sickness behavior Jessica Osterhout (USA) 2:45pm-3:00pm | Discussion | Peripheral Neuroimmunology Chairs: Nader Ghasemlou (Canada) & Phillip Popovich (USA) 1:00pm-1:15pm | Nociceptor neuron recognition of microbes in host defense and immunity Isaac Chiu (USA) 1:15pm-1:30pm | Pain neurons control cancer immunosurveillance Sebastien Talbot (Canada) 1:30pm-1:45pm | Neuro-immune interactions in the gut Daniel Mucida (USA) Oral Presentations 1:45pm-2:00pm | 13 Multimodal control of dendritic cell functions by nociceptors Pavel Hanč (USA) B cells in Neuroinflammation Chairs: Amit Bar-Or (USA) & Heinz Wiendl (Germany) 2:00pm-2:15pm | Plasmablasts in a model of CNS autoimmunity: from biology to therapy Luc Vallières 2:15pm-2:30pm | #345 T:B cell communication in ectopic lymphoid follicles in CNS autoimmunity Anneli Peters (Germany) 2:30pm-2:45pm | #44 T-bet+ Memory B Cells Induce Disease Relapses in Experimental Autoimmune Encephalomyelitis Rajiv Jain (Canada) 2:45pm-3:00pm | #55 B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice Angela A. Wang (Canada) | Learning about Neuroimmunology through ALS - Sponsored by ALS Society of Quebec Chairs: Chrstine Vande Velde (Canada) & Jean-Pierre Julien (Canada) 1:00pm-1:20pm | The title of my talk will be: Microglia and macrophages for ALS progression. Séverine Boillée (France) 1:20pm-1:40pm | Modulating myeloid cells in ALS by targeting α5 integrin Bahareh Ajami (USA) 1:40pm-2:00pm | Targeting innate immune genes translation in ALS Jasna Kriz (Canada) 2:00pm-2:20pm | Peripheral and resident immune cells crosstalk in ALS Cristina Limatola (Italy) 2:20pm-2:40pm | Role of endogenous retroviruses in Amyotrophic Lateral Sclerosis Avindra Nath (USA) 2:40pm-3:00pm | Restoring glial functions at the neuromuscular synapse: a clinical target in ALS Richard Robitaille (Canada) |
ISNI KEYNOTE LECTURE3:15pm - 4:15pm |
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| The Immunology Lecture Chair: Francisco Quintana (USA) Checkpoints of CNS autoimmunity: from the perspective of an autoaggressive T cell Alexander Flügel (Germany) |
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POSTER SESSION 34:15pm - 6:15pm CNS barriers |
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