Day 4 | August 23
ISNI DAY 3 - TUESDAY AUGUST 22 |
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PLENARY SESSION8:00am - 10:00am |
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| Pathological mechanisms in autoimmune diseases of the nervous system Chairs: Christopher Power (Canada) & Thomas Korn (Germany) 8:00am-8:30am | EBV-Mediated Molecular Mimicry in Multiple Sclerosis William H. Robison (USA) 8:30am-9:00am | B cells, BAFF and CNS inflammation Jen Gommerman (Canada) 9:00am-9:30am | Antibody Defined CNS Autoimmune Neurological Disorders: Discovery to Near Cure Sean Pittock (USA) 9:30am-10:00am | New insights into how brain and periphery communicate Jonathan Kipnis (USA) |
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| Coffee Break | 10:00am-10:30am | |||
MORNING BREAKOUT SESSIONS10:30am - 12:00pm |
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| Involvement of glial cells in neuroinflammation Chairs: Nathalie Arbour (Canada) & Michael Simons (Germany) 10:30am-10:48am | Regulatory glial cell-cell interactions Francisco Quintana (USA) 10:48am-11:06am | Insights from a unique model to study de novo myelination Zhigang He (USA) 11:06am-11:24am | What is the role of reactive astrocytes in disease? Shane Liddelow (USA) Oral Presentations 11:24am-11:42am | #116 Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis Cameron S. McAlpine (USA) 11:42am-12:00pm | #9 Fibulin-2 impedes oligodendrogenesis through engaging the Notch signaling pathway Samira Ghorbani (Canada) | Influence of sex on neuroinflammation Chairs: Lisa Osborne (Canada) & Ari Waisman (Germany) 10:30am-10:48am | Sex differences in microglial metabolism and implications for neural development Staci Bilbo (USA) 10:48am-11:06am | Female sex exacerbates age-related changes in microglia Marina Lynch (Ireland) 11:06am-11:24am | Adiposity interacts with female sex to promote T helper 1 inflammation and autoimmunity Shannon Dunn (Canada) 11:24am-11:42am | Biological sex as a determinant in inflammatory T cell responses in chronic CNS autoimmunity Manu Rangachari (Canada) Oral Presentations 11:42am-12:00pm | #305 Role of sex, gonadal hormones and dutasteride treatment on central and peripheral inflammation in a mouse model of Parkinson’s disease. Amandine Isenbrandt (Canada) |
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| Lunch Break | 12:00pm-1pm | |||
AFTERNOON BREAKOUT SESSIONS1:00pm - 3:00pm |
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| Microglia in neural development, remodelling, and protection Chairs: Staci Bilbo (USA) & David Gosselin (Canada) 1:00pm-1:15pm | Diverse macrophages sense and govern brain environment Takahiro Masuda (Japan) 1:15pm-1:30pm | The many roles of microglia in the pathogenesis of neurodegeneration Rosa Paolicelli (Switzerland) 1:30pm-1:45pm | Roles of dark microglia during normal brain development Marie-Eve Tremblay (Canada) 1:45pm-2:00pm | Microglia are required for remyelination Jason Plemel (Canada) Oral Presentations 2:00pm-2:15pm | #289 Avb8-Tgfb1 signaling in brain vascular and microglial development Gabriel L. McKinsey (USA) 2:15pm-2:30pm | #128 Stearoyl-CoA desaturase-1 impairs the regenerative and anti-inflammatory properties of microglia and T cells in the brain Jeroen F.J. Bogie (Belgium) 2:30pm-2:45pm | #17 APOE4 Impairs Microglia Response to Neurodegeneration in Alzheimer’s Disease Neta Rosenzweig (USA) 2:45pm-3:00pm | #83 Microglia coordinate cellular interactions during spinal cord repair in mice Faith H. Brennan (Canada) | T cells in neurological diseases Chairs: Shannon Dunn (Canada) & Manu Rangachari (Canada) 1:00pm-1:15pm | Stranger Things about IL-12 and IL-23 Burkhard Becher (Switzerland) 1:15pm-1:30pm | Th17 cells- to be, or not be, is the question before us Vijay Kuchroo (USA) 1:30pm-1:45pm | IL-17 controls CNS autoimmunity through the intestinal microbiome Ari Waisman (Germany) Oral Presentations 1:45pm-2:00pm | #11 TCF1 is a determinant of homeostatic versus pathogenic Th17 cell state Ana C. Anderson (USA) 2:00pm-2:15pm | #193 Tissue-resident memory T cells sustain the chronic phase of experimental autoimmune encephalomyelitis Frederick Masson (France) 2:15pm-2:30pm | #16 Brain endothelial antigen presentation detains CD8 T cells at the blood-brain barrier and contributes to its breakdown Javier Pareja (Switzerland) 2:30pm-2:45pm | #355 Impaired CNS Immunosurveillance by CCR7+ CD4 T cells during chronic neuroinflammation Elizaldi Sonny (USA) 2:45pm-3:00pm | #102 The transcription factor c-Maf promotes immunoregulation of CD8+ T cells in multiple sclerosis Norio Chihara (Japan) | Biomarkers of neuroinflammation Chairs: Catherine Larochelle (Canada) & Martina Absinta (Italy) 1:00pm-1:15pm | Compartment specific (endo)phenotyping of neuroinflammation Heinz Wiendl (Germany) 1:15pm-1:30pm | Biomarkers of relapsing course in MOG antibody-associated disease Fabienne Brilot (Australia) 1:30pm-1:45pm | What Information Does the Serum Biomarker Neurofilament Light Chain Offer in the Management of Multiple Sclerosis? Mark Freedman (Canada) Oral Presentations 1:45pm-2:00pm | #59 CanProCo Study; Examining Prognostic Protein Biomarkers in Sera and Plasma from Multiple Sclerosis Patients Fiona Tea (Canada) 2:00pm-2:15pm | #286 Machine learning identifies a combination of immunological and clinical parameters as the best predictor of MS disease progression Stephanie Zandee (Canada) 2:15pm-2:30pm | #266 Biomarkers in autoimmune diseases of the central nervous system : the autoimmune encephalitis challenge Chloe Bost (France) 2:30pm-2:45pm | #310 Interleukin-7 receptor alpha is increased on CD4+ effector T cells in clinically established multiple sclerosis Raphael Schneider (Canada) 2:45pm-3:00pm | #319 Immunosenescence trajectories in diverse human populations: evaluation of immune age towards personalized therapies Hanane Touil (USA) | Learning about neuroimmunology through Parkinson's disease - Sponsored by ASAP Chairs: John Lukens (USA) & Michael Heneka (Germany) 1:00pm-1:24pm | Parkinson’s Disease-proteins regulate the transition from innate to adaptive immunity Michel Desjardins (Canada) 1:24pm-1:48pm | Innate Immune Dysfunction in People with Parkinson’s and Pre-clinical Models of disease Malu Tansey (USA) 1:48pm-2:12pm | Unveiling the Enigma: Exploring Neuroinflammation's Impact on Parkinson's Disease Ted Dawson (USA) 2:12pm-2:36pm | Microglia iron overload and ferroptosis cause neurodegeneration Timothy Hammond (USA) 2:36pm-3:00pm | Brain-to-gut trafficking of alpha-Synuclein by CD11c+ macrophages in Parkinson’s Disease Rhonda McFleder (Germany) |
ISNI KEYNOTE LECTURE3:15pm - 4:15pm |
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| The Rita Levi-Montalcini Neurobiology Lecture Chair: Alexandre Prat (Canada) Inflammation and Neurodegeneration in multiple sclerosis: A single and common pathway? Hans Lassmann (Austria) |
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POSTER SESSION 24:15pm - 6:15pm Biomarkers of neuroinflammation |
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ISNI GENERAL ASSEMBLY6:15pm - 7:15pm |
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